Chronic Insomnia: How to Combine CBT-I + Medication (AASM New Guideline) (2026)

A new clinical practice guideline from the American Academy of Sleep Medicine provides evidence-based recommendations on combining behavioral-psychological and pharmacological therapies for chronic insomnia disorder in adults. The guideline, published in the Journal of Clinical Sleep Medicine, offers insights into the combined use of these treatments, addressing a gap in previous guidelines that did not evaluate the comparative efficacy of combination therapy. The AASM suggests that Cognitive Behavioral Therapy for Insomnia (CBT-I) is the most effective first-line treatment, but combining it with medication may offer modest benefits for specific sleep outcomes. This recommendation emphasizes shared decision-making, considering patient values and preferences. The guideline was developed through a systematic review, meta-analysis, and evaluation of combination therapy's benefits and harms, with input from sleep medicine experts and public comment. It was affirmed by several medical associations and endorsed by various sleep-related organizations. The authors, including Dr. Daniel J. Buysse, highlight the importance of patient-centered decision-making in insomnia treatment, while also noting the potential risks associated with pharmacotherapy. The guideline provides valuable insights for healthcare professionals managing chronic insomnia, promoting informed and personalized treatment approaches.

Chronic Insomnia: How to Combine CBT-I + Medication (AASM New Guideline) (2026)
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